<xbrl xmlns="http://www.xbrl.org/2003/instance" xmlns:e="http://xbrl.dcca.dk/sob" xmlns:b="http://xbrl.dcca.dk/entryBalanceSheetAccountFormIncomeStatementByNature" xmlns:h="http://xbrl.dcca.dk/mrv" xmlns:f="http://xbrl.dcca.dk/arr" xmlns:d="http://xbrl.dcca.dk/cmn" xmlns:g="http://xbrl.dcca.dk/fsa" xmlns:c="http://xbrl.dcca.dk/gsd" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xbrli="http://www.xbrl.org/2003/instance" xmlns:iso4217="http://www.xbrl.org/2003/iso4217" xmlns:xbrldi="http://xbrl.org/2006/xbrldi" xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://xbrl.dcca.dk/entryBalanceSheetAccountFormIncomeStatementByNature http://archprod.service.eogs.dk/taxonomy/20221001/entryDanishGAAPBalanceSheetAccountFormIncomeStatementByNatureIncludingManagementsReviewStatisticsAndTax20221001.xsd"><link:schemaRef xlink:type="simple" xlink:href="http://archprod.service.eogs.dk/taxonomy/20221001/entryDanishGAAPBalanceSheetAccountFormIncomeStatementByNatureIncludingManagementsReviewStatisticsAndTax20221001.xsd" /><c:NameOfSubmittingEnterprise contextRef="c179" xml:lang="en">BDO Statsautoriseret revisionsaktieselskab</c:NameOfSubmittingEnterprise><c:AddressOfSubmittingEnterpriseStreetAndNumber contextRef="c179" xml:lang="en">Kystvejen 29</c:AddressOfSubmittingEnterpriseStreetAndNumber><c:AddressOfSubmittingEnterprisePostcodeAndTown contextRef="c179" xml:lang="en">DK-8000 Aarhus C</c:AddressOfSubmittingEnterprisePostcodeAndTown><c:IdentificationNumberCvrOfSubmittingEnterprise contextRef="c179" xml:lang="en">20222670</c:IdentificationNumberCvrOfSubmittingEnterprise><c:InformationOnTypeOfSubmittedReport contextRef="c179">Årsrapport</c:InformationOnTypeOfSubmittedReport><c:DateOfGeneralMeeting contextRef="c179">2023-03-24</c:DateOfGeneralMeeting><c:NameAndSurnameOfChairmanOfGeneralMeeting contextRef="c179" xml:lang="en">Simon Mølgaard Jensen</c:NameAndSurnameOfChairmanOfGeneralMeeting><c:NameOfReportingEntity contextRef="c179" xml:lang="en">Teitur Trophics ApS</c:NameOfReportingEntity><c:AddressOfReportingEntityStreetName contextRef="c179" xml:lang="en">c/o Simon Mølgaard Jensen, Hjortshøjvangen 112</c:AddressOfReportingEntityStreetName><c:AddressOfReportingEntityPostCodeIdentifier contextRef="c179" xml:lang="en">8530 Hjortshøj</c:AddressOfReportingEntityPostCodeIdentifier><d:TypeOfAuditorAssistance contextRef="c179" xml:lang="en">Andre erklæringer uden sikkerhed</d:TypeOfAuditorAssistance><c:IdentificationNumberCvrOfReportingEntity contextRef="c179" xml:lang="en">41058439</c:IdentificationNumberCvrOfReportingEntity><c:DateOfFoundationOfReportingEntity contextRef="c179">2020-01-08</c:DateOfFoundationOfReportingEntity><c:RegisteredOfficeOfReportingEntity contextRef="c179" xml:lang="en">Aarhus</c:RegisteredOfficeOfReportingEntity><c:ReportingPeriodStartDate contextRef="c179">2022-01-01</c:ReportingPeriodStartDate><c:ReportingPeriodEndDate contextRef="c179">2022-12-31</c:ReportingPeriodEndDate><c:PrecedingReportingPeriodStartDate contextRef="c179">2021-01-01</c:PrecedingReportingPeriodStartDate><c:PredingReportingPeriodEndDate contextRef="c179">2021-12-31</c:PredingReportingPeriodEndDate><d:NameOfAuditFirm contextRef="c179" xml:lang="en">BDO Statsautoriseret revisionsaktieselskab</d:NameOfAuditFirm><c:AddressOfAuditorStreetName contextRef="c179" xml:lang="en">Kystvejen</c:AddressOfAuditorStreetName><c:AddressOfAuditorStreetBuildingIdentifier contextRef="c179" xml:lang="en">29</c:AddressOfAuditorStreetBuildingIdentifier><c:AddressOfAuditorPostCodeIdentifier contextRef="c179" xml:lang="en">8000</c:AddressOfAuditorPostCodeIdentifier><c:AddressOfAuditorDistrictName contextRef="c179" xml:lang="en">Aarhus C</c:AddressOfAuditorDistrictName><e:PlaceOfSignatureOfStatement contextRef="c179" 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unitRef="u1" decimals="0">1197306</g:ShorttermReceivables><g:ShorttermReceivables contextRef="c178" unitRef="u1" decimals="0">1867118</g:ShorttermReceivables><g:CashAndCashEquivalents contextRef="c177" unitRef="u1" decimals="0">3904555</g:CashAndCashEquivalents><g:CashAndCashEquivalents contextRef="c178" unitRef="u1" decimals="0">7194321</g:CashAndCashEquivalents><g:Assets contextRef="c177" unitRef="u1" decimals="0">5108528</g:Assets><g:Assets contextRef="c178" unitRef="u1" decimals="0">9074772</g:Assets><g:ContributedCapital contextRef="c177" unitRef="u1" decimals="0">40000</g:ContributedCapital><g:ContributedCapital contextRef="c178" unitRef="u1" decimals="0">40000</g:ContributedCapital><g:RetainedEarnings contextRef="c177" unitRef="u1" decimals="0">-16988846</g:RetainedEarnings><g:RetainedEarnings contextRef="c178" unitRef="u1" decimals="0">-11454670</g:RetainedEarnings><g:Equity contextRef="c177" unitRef="u1" decimals="0">-16948846</g:Equity><g:Equity contextRef="c178" unitRef="u1" 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decimals="0">-16988846</g:Equity><g:AverageNumberOfEmployees contextRef="c179" unitRef="u0" decimals="0">2</g:AverageNumberOfEmployees><g:AverageNumberOfEmployees contextRef="c180" unitRef="u0" decimals="0">3</g:AverageNumberOfEmployees><g:WagesAndSalaries contextRef="c179" unitRef="u1" decimals="0">1511626</g:WagesAndSalaries><g:WagesAndSalaries contextRef="c180" unitRef="u1" decimals="0">1763591</g:WagesAndSalaries><g:PostemploymentBenefitExpense contextRef="c179" unitRef="u1" decimals="0">188124</g:PostemploymentBenefitExpense><g:PostemploymentBenefitExpense contextRef="c180" unitRef="u1" decimals="0">139500</g:PostemploymentBenefitExpense><g:SocialSecurityContributions contextRef="c179" unitRef="u1" decimals="0">17792</g:SocialSecurityContributions><g:SocialSecurityContributions contextRef="c180" unitRef="u1" decimals="0">27459</g:SocialSecurityContributions><g:OtherEmployeeExpense contextRef="c179" unitRef="u1" decimals="0">17524</g:OtherEmployeeExpense><g:OtherEmployeeExpense contextRef="c180" unitRef="u1" decimals="0">15580</g:OtherEmployeeExpense><g:EmployeeBenefitsExpense contextRef="c179" unitRef="u1" decimals="0">1735066</g:EmployeeBenefitsExpense><g:EmployeeBenefitsExpense contextRef="c180" unitRef="u1" decimals="0">1946130</g:EmployeeBenefitsExpense><g:CurrentTaxExpense contextRef="c179" unitRef="u1" decimals="0">-952112</g:CurrentTaxExpense><g:CurrentTaxExpense contextRef="c180" unitRef="u1" decimals="0">-1675946</g:CurrentTaxExpense><g:PropertyPlantAndEquipmentGross contextRef="c499" unitRef="u1" decimals="0">19999</g:PropertyPlantAndEquipmentGross><g:PropertyPlantAndEquipmentGross contextRef="c501" unitRef="u1" decimals="0">19999</g:PropertyPlantAndEquipmentGross><g:AccumulatedImpairmentLossesAndDepreciationOfPropertyPlantAndEquipment contextRef="c499" unitRef="u1" decimals="0">6666</g:AccumulatedImpairmentLossesAndDepreciationOfPropertyPlantAndEquipment><g:DepreciationOfPropertyPlantAndEquipment contextRef="c497" unitRef="u1" decimals="0">6666</g:DepreciationOfPropertyPlantAndEquipment><g:AccumulatedImpairmentLossesAndDepreciationOfPropertyPlantAndEquipment contextRef="c501" unitRef="u1" decimals="0">13332</g:AccumulatedImpairmentLossesAndDepreciationOfPropertyPlantAndEquipment><g:PropertyPlantAndEquipment contextRef="c501" unitRef="u1" decimals="0">6667</g:PropertyPlantAndEquipment><g:LongtermLiabilitiesOtherThanProvisionsDueAfterFiveYearsAndMore contextRef="c177" unitRef="u1" decimals="0">0</g:LongtermLiabilitiesOtherThanProvisionsDueAfterFiveYearsAndMore><g:ClassOfReportingEntity contextRef="c179">Regnskabsklasse B</g:ClassOfReportingEntity><g:SelectedElementsFromReportingClassC contextRef="c179">true</g:SelectedElementsFromReportingClassC><g:AccountingPoliciesAreUnchangedFromPreviousPeriod contextRef="c179">true</g:AccountingPoliciesAreUnchangedFromPreviousPeriod><e:IdentificationOfApprovedAnnualReport contextRef="c179">Today the Board of Directors and Executive Board have discussed and approved the Annual Report of Teitur Trophics ApS for the financial year 1 January  - 31 December 2022.






</e:IdentificationOfApprovedAnnualReport><e:ConfirmationThatAnnualReportIsPresentedInAccordanceWithRequirementsProvidedForByLegislationAnyStandardsAndRequirementsProvidedByArticlesOfAssociationOrByAgreement contextRef="c179">The Annual Report is presented in accordance with the Danish Financial Statements Act.






</e:ConfirmationThatAnnualReportIsPresentedInAccordanceWithRequirementsProvidedForByLegislationAnyStandardsAndRequirementsProvidedByArticlesOfAssociationOrByAgreement><e:ConfirmationThatFinancialStatementGivesTrueAndFairViewOfAssetsLiabilitiesEquityFinancialPositionAndResults contextRef="c179">In our opinion the Financial Statements give a true and fair view of the Company's assets, liabilities and financial position at 31 December 2022 and of the results of the Company's operations for the financial year 1 January  - 31 December 2022.







</e:ConfirmationThatFinancialStatementGivesTrueAndFairViewOfAssetsLiabilitiesEquityFinancialPositionAndResults><e:ManagementsStatementAboutManagementsReview contextRef="c179">The Management Commentary includes in our opinion a fair presentation of the matters dealt with in the Commentary.








</e:ManagementsStatementAboutManagementsReview><e:ConfirmationThatFinancialStatementsAreExemptedFromAuditing contextRef="c179">The Board of Directors and Executive Board remain of the opinion that the conditions for opting out of audit have been fulfilled. 



</e:ConfirmationThatFinancialStatementsAreExemptedFromAuditing><e:RecommendationForApprovalOfAnnualReportByGeneralMeeting contextRef="c179">We recommend the Annual Report be approved at the Annual General Meeting.



</e:RecommendationForApprovalOfAnnualReportByGeneralMeeting><f:AddresseeOfAuditorsReportOnOtherReport contextRef="c179">To the Shareholders of Teitur Trophics ApS




</f:AddresseeOfAuditorsReportOnOtherReport><f:DescriptionOfOtherEngagement contextRef="c179">We have compiled these Financial Statements of Teitur Trophics ApS for the financial year 1 January - 31 December 2022 based on the Company's accounting records and other information provided by Management. 


These Financial Statements comprise income statement, balance sheet, statement of changes in equity, notes and accounting policies. 


We performed this compilation engagement in accordance with the International Standard, Compilation Engagements. 


We have applied our professional expertise to assist Management in the preparation and presentation of these Financial Statements in accordance with the Danish Financial Statements Act. We have complied with relevant statutory provisions of the Danish Audit Act and International Ethics Standards Board for Accountants’ International Code of Ethics for Professional Accountants (including International Independence Standards) (IESBA Code), including principles of integrity, objectivity, professional behaviour, and due care. 


These Financial Statements and the accuracy and completeness of the information used to compile these Financial Statements are Management’s responsibility. 


Since an engagement to compile financial information is not an assurance engagement, we are not required to verify the accuracy or completeness of the information provided by Management to us to compile these Financial Statements. Accordingly, we do not express an audit opinion or a review conclusion on whether these Financial Statements are prepared in accordance with the Danish Financial Statements Act. 

</f:DescriptionOfOtherEngagement><h:DescriptionOfPrimaryActivitiesOfEntity contextRef="c179">Principal activities




The company's purpose is to research, develop, produce and sell biotechnological products and medicinal products. 


</h:DescriptionOfPrimaryActivitiesOfEntity><h:DescriptionOfDevelopmentInActivitiesAndFinancialAffairs contextRef="c179">Development in activities and financial and economic position




The company's income statement for the financial year 2022 shows a loss of 5,534 DKK ('000) and the company's balance sheet per 31 December 2022 shows an equity of -16,949 DKK ('000).  The result is characterized by the fact that the company is in the start-up phase with limited operations and costs for research. The company's financial position complies with management's expectations and is considered satisfactory.  The company has obtained external capital and liquidity, and it is management's expectation that this can cover the company's continued research and re-establish the company's share capital until research activities are completed, and future operation will be able to generate profit.  Regarding to going concern, the company is therefore dependent on continued financing from lenders. However, redemption or conversion of the loan into shares can take place no earlier than the end of 2024.  Tax receivables 952 DKK ('000) has been included as the company applies for payment under section 8 of the Tax Assessment Act - the tax credit scheme.






</h:DescriptionOfDevelopmentInActivitiesAndFinancialAffairs><h:DescriptionOfSignificantEventsOccurringAfterEndOfReportingPeriod contextRef="c179">Significant events after the end of the financial year




No events have occurred after the end of the financial year of material importance for the Company's financial position. 


</h:DescriptionOfSignificantEventsOccurringAfterEndOfReportingPeriod><g:DisclosureOfEquity contextRef="c179">Share capital
Retained earnings
Total




Equity at 1 January 2022 
40.000
-11.454.670
-11.414.670






Proposed profit allocation  

-5.534.176
-5.534.176






Equity at 31 December 2022 
40.000
-16.988.846
-16.948.846














</g:DisclosureOfEquity><g:DisclosureOfEmployeeBenefitsExpense contextRef="c179">2022
2021


DKK
DKK






Staff costs


1

Average number of employees
2
3







Wages and salaries 
1.511.626
1.763.591


Pensions 
188.124
139.500


Social security costs 
17.792
27.459


Other staff costs 
17.524
15.580








1.735.066
1.946.130



</g:DisclosureOfEmployeeBenefitsExpense><g:DisclosureOfPropertyPlantAndEquipment contextRef="c179">Property, plant and equipment




3



Other plant, machinery tools and equipment


Cost at 1 January 2022 
19.999
Cost at 31 December 2022 
19.999


Depreciation and impairment losses at 1 January 2022 
6.666
Depreciation for the year 
6.666
Depreciation and impairment losses at 31 December 2022 
13.332


Carrying amount at 31 December 2022 
6.667



</g:DisclosureOfPropertyPlantAndEquipment><g:DisclosureOfLongtermLiabilities contextRef="c179">Long-term liabilities


4


31/12 2022
Repayment
Debt outstanding
31/12 2021
total liabilities
next year
after 5 years
total liabilities





Convertible and interest-bearing debt instruments 
20.756.053
0
0
19.746.974
532.100
532.100.01






20.756.053
0
0
19.746.974






The Company has entered into a convertible loan of a carrying amount of DKK (’000) 20,756 at 31 December 2022. Conversion into shares on one of three loans must take place at the latest three years after the last tranche has been paid out, and the deadline is therefore expected to be end 2024. Rate shall correspond to the market price pr. share as determined by the Lender and the Company. The conversion rate can in no event be lower than par value of the shares.


</g:DisclosureOfLongtermLiabilities><g:DisclosureOfContingentAssets contextRef="c179">Contingent assets
The company has unutilised tax losses amounting to 10,211 DKK ('000), which are not recognised due to uncertainty related to future utilization. 
</g:DisclosureOfContingentAssets><g:DisclosureOfContingentLiabilities contextRef="c179">Contingent liabilities

The company has signed lease agreements with a non-terminability period which expires at 31 March 2023. The total liability in the lease period is 70 DKK ('000).
</g:DisclosureOfContingentLiabilities><g:DisclosureOfAnyUnusualMatters contextRef="c179">Prerequisites for going concern
6


The company has lost its share capital and has entered into a convertible loan of a carrying amount of DKK (’000) 20,756 at 31 December 2022. Therefore, it is dependent on continuing to receive such financing from lenders. Redemption or conversion of the loan into shares can take place no earlier than the end of 2024.

</g:DisclosureOfAnyUnusualMatters><g:InformationOnReportingClassOfEntity contextRef="c179">The Annual Report of Teitur Trophics ApS for 2022 has been presented in accordance with the provisions of the Danish Financial Statements Act for enterprises in reporting class B and certain provisions applying to reporting class C. 
Regnskabsklasse B1
true
true

The Annual Report is prepared consistently with the accounting principles applied last year. 


</g:InformationOnReportingClassOfEntity><g:DescriptionOfMethodsOfRecognitionAndMeasurementBasisOfOtherOperatingIncome contextRef="c179">Other operating income




Other operating income includes items of a secondary nature in relation to the Group’s and the Company’s activities, including profit from sale of intangible and tangible fixed assets. In addition, profit from sale of intangible and tangible fixed assets as well as business interruption and conflict compensations are included. Compensations are recognised when the income is deemed to be realisable. 


</g:DescriptionOfMethodsOfRecognitionAndMeasurementBasisOfOtherOperatingIncome><g:DescriptionOfMethodsOfRecognitionAndMeasurementBasisOfCostOfSales contextRef="c179">Research and development costs




Research and development costs include labatory materials, patent costs, clinical studies and other costs relating to the company's research and development activies. 


</g:DescriptionOfMethodsOfRecognitionAndMeasurementBasisOfCostOfSales><g:DescriptionOfMethodsOfRecognitionAndMeasurementBasisOfExternalExpenses contextRef="c179">Other external expenses



Other external expenses include cost of sales, administration etc. 


</g:DescriptionOfMethodsOfRecognitionAndMeasurementBasisOfExternalExpenses><g:DescriptionOfMethodsOfRecognitionAndMeasurementBasisOfEmployeeBenefitExpense contextRef="c179">Staff costs




Staff costs comprise wages and salaries, including holiday pay, pensions, and other costs for social security etc., for the company’s employees. Repayments from public authorities are deducted from staff costs. 


</g:DescriptionOfMethodsOfRecognitionAndMeasurementBasisOfEmployeeBenefitExpense><g:DescriptionOfMethodsOfRecognitionAndMeasurementBasisOfFinanceIncomeAndExpenses contextRef="c179">Financial income and expenses





Financial income and expenses include interest income and expenses, realised and unrealised gains and losses arising from debt and transactions in foreign currencies. Financial income and expenses are recognised in the Income Statement by the amounts that relate to the financial year. 


</g:DescriptionOfMethodsOfRecognitionAndMeasurementBasisOfFinanceIncomeAndExpenses><g:DescriptionOfMethodsOfRecognitionAndMeasurementBasisOfTaxExpenses contextRef="c179">Tax





The tax for the year, which consists of the current tax for the year and changes in deferred tax, is recognised in the income statement by the portion that may be attributed to the profit for the year, and is recognised directly in the equity by the portion that may be attributed to entries directly to the equity. 


</g:DescriptionOfMethodsOfRecognitionAndMeasurementBasisOfTaxExpenses><g:DescriptionOfMethodsOfRecognitionAndMeasurementBasisOfPropertyPlantAndEquipment contextRef="c179">Tangible fixed assets





Plant, fixtures and equipment are measured at cost less accumulated depreciation and impairment losses. 



The depreciation base is cost less estimated residual value after end of useful life. 



The cost includes the acquisition price and costs incurred directly in connection with the acquisition until the time when the asset is ready to be used.  




Straight-line depreciation is provided on the basis of an assessment of the expected useful lives of the assets and their residual value: 




Useful lifeResidual value





Other plant, fixtures and equipment  3 years 0%




Profit or loss on disposal of tangible fixed assets is stated as the difference between the sales price less selling costs and the carrying amount at the time of sale. Profit or loss is recognised in the income statement as other operating income or other operating expenses. 



</g:DescriptionOfMethodsOfRecognitionAndMeasurementBasisOfPropertyPlantAndEquipment><g:DescriptionOfMethodsOfAmortisationOfNoncurrentAssets contextRef="c179">Impairment of fixed assets





The carrying amount of tangible assets are valued on an annual basis for indications of impairment other than that reflected by amortisation and depreciation.  



In the event of impairment indications, an impairment test is made for each asset or group of assets, respectively. If the recoverable amount is lower than the carrying amount, the asset is written down to the carrying amount.



The recoverable amount is calculated at the higher of net selling price and capital value. The capital value is determined as the fair value of the expected net cash flows from the use of the asset or group of assets and the expected net cash flows from sale of the asset or group of assets after the end of its useful life.  



</g:DescriptionOfMethodsOfAmortisationOfNoncurrentAssets><g:DescriptionOfMethodsOfRecognitionAndMeasurementBasisOfReceivables contextRef="c179">Receivables





Receivables are measured at amortised cost which usually corresponds to nominal value. The value is written down to meet expected losses. 


</g:DescriptionOfMethodsOfRecognitionAndMeasurementBasisOfReceivables><g:DescriptionOfMethodsOfRecognitionAndMeasurementBasisOfDeferredIncomeAssets contextRef="c179">Accruals, assets





Accruals recognised as assets include costs incurred relating to the subsequent financial year. 


</g:DescriptionOfMethodsOfRecognitionAndMeasurementBasisOfDeferredIncomeAssets><g:DescriptionOfMethodsOfRecognitionAndMeasurementBasisOfTaxPayablesAndDeferredTax contextRef="c179">Tax payable and deferred tax




Current tax liabilities and receivable current tax are recognised in the Balance Sheet as the calculated tax on the taxable income for the year, adjusted for tax on the taxable income for previous years and taxes paid on account. 



Deferred tax is measured on the temporary differences between the carrying amount and the tax value of assets and liabilities.



Deferred tax assets, including the tax value of tax loss carry-forwards, are measured at the expected realisable value of the asset, either by set-off against tax on future earnings or by set-off against deferred tax liabilities within the same legal tax entity. 



Deferred tax is measured on the basis of the tax rules and tax rates that under the legislation in force on the Balance Sheet date will be applicable when the deferred tax is expected to crystallise as current tax. Any changes in the deferred tax resulting from changes in tax rates, are recognised in the income statement, except from items recognised directly in equity. 


</g:DescriptionOfMethodsOfRecognitionAndMeasurementBasisOfTaxPayablesAndDeferredTax><g:DescriptionOfMethodsOfRecognitionAndMeasurementBasisOfLiabilitiesOtherThanProvisions contextRef="c179">Liabilities





Financial liabilities are recognised at the time of borrowing by the amount of proceeds received less borrowing costs. In subsequent periods, the financial liabilities are measured at amortised cost equal to the capitalised value when using the effective interest, the difference between the proceeds and the nominal value being recognised in the Income Statement over the term of loan. 



Amortised cost for short-term liabilities usually corresponds to the nominal value. 



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